Twelve years ago I was on a British Airways flight to Frankfurt when I had the pleasure of sitting next to some college-aged Deadhead. When the time came for beverages, I asked for a rum-and-coke and my pal asked for three cans of whatever beer they were serving. He then proceeded to shotgun the cans in succession. I asked why he was doing that and his reply was, "Shotgunning these beers'll get you wasted quicker because we're at a higher altitude, dude."
I hadn't the heart to tell him that the cabin was pressurized.